Nejat K Egilmez Selected Research

Interleukin-12 (IL 12)

10/2019	Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment.
1/2018	Intravaginal Administration of Interleukin 12 during Genital Gonococcal Infection in Mice Induces Immunity to Heterologous Strains of Neisseria gonorrhoeae.
1/2018	Enhanced gut barrier integrity sensitizes colon cancer to immune therapy.
1/2016	Tolerogenic Phenotype of IFN-γ-Induced IDO+ Dendritic Cells Is Maintained via an Autocrine IDO-Kynurenine/AhR-IDO Loop.
5/2014	Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors.
12/2013	Enhancement of adaptive immunity to Neisseria gonorrhoeae by local intravaginal administration of microencapsulated interleukin 12.
7/2012	Chemoimmunotherapy as long-term maintenance therapy for cancer.
10/2011	Chronic chemoimmunotherapy achieves cure of spontaneous murine mammary tumors via persistent blockade of posttherapy counter-regulation.
7/2011	Dichotomous effects of IFN-γ on dendritic cell function determine the extent of IL-12-driven antitumor T cell immunity.
6/2011	Nitric oxide short-circuits interleukin-12-mediated tumor regression.

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Nejat K Egilmez Research Topics

Disease

45	Neoplasms (Cancer) 10/2021 - 04/2002
6	Neoplasm Metastasis (Metastasis) 10/2019 - 01/2003
5	Colitis 01/2022 - 06/2015
4	Colonic Neoplasms (Colon Cancer) 01/2021 - 04/2015
4	Breast Neoplasms (Breast Cancer) 01/2020 - 02/2004
3	Inflammation (Inflammations) 01/2022 - 07/2015
3	Obesity 10/2021 - 11/2018
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2018 - 08/2015
3	Infections 01/2018 - 12/2013
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 01/2020
2	Adenocarcinoma 10/2020 - 10/2019
2	Carcinogenesis 11/2018 - 01/2017
2	Lung Neoplasms (Lung Cancer) 11/2018 - 05/2002
2	Gonorrhea 01/2018 - 12/2013
2	Reinfection 01/2018 - 12/2013
2	Schistosomiasis (Bilharziasis) 01/2015 - 05/2004
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2021
1	Intestinal Polyps 01/2021
1	Dysbiosis 01/2020
1	Reproductive Tract Infections 01/2018
1	Weight Loss (Weight Reduction) 08/2015
1	Polyps 07/2015
1	Pathologic Complete Response 05/2014
1	Communicable Diseases (Infectious Diseases) 12/2013

Drug/Important Bio-Agent (IBA)

25	Interleukin-12 (IL 12)IBA 10/2019 - 05/2002
13	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2016 - 12/2002
11	CytokinesIBA 04/2015 - 05/2002
6	Interleukin-10 (Interleukin 10)IBA 11/2018 - 06/2006
5	AntibodiesIBA 01/2019 - 10/2005
4	Transforming Growth Factor beta (TGF-beta)IBA 01/2018 - 02/2007
3	EnzymesIBA 01/2020 - 12/2002
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2018 - 12/2013
3	Immunoglobulin G (IgG)IBA 01/2018 - 12/2013
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2018 - 08/2015
3	Interferon-gamma (Interferon, gamma)IBA 01/2018 - 05/2002
3	PolymersIBA 12/2013 - 12/2004
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2007 - 02/2004
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2005
2	Anthocyanins (Anthocyanin)IBA 01/2021 - 01/2020
2	Fatty Acid-Binding ProteinsIBA 11/2018 - 01/2018
2	Immunoglobulin A (IgA)IBA 01/2018 - 12/2013
2	Serum Amyloid A Protein (Serum Amyloid A)IBA 08/2015 - 01/2004
2	ChemokinesIBA 06/2015 - 01/2003
2	VaccinesIBA 01/2015 - 12/2013
2	SuspensionsIBA 07/2012 - 02/2004
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 07/2012 - 10/2011
1	Phospholipases A2 (Phospholipase A2)IBA 01/2022
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2022
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2022
1	Unsaturated Dietary FatsIBA 10/2021
1	OilsIBA 10/2021
1	Linoleic AcidsIBA 10/2021
1	Dietary Fats (Dietary Fat)IBA 10/2021
1	Interleukin-17 (Interleukin 17)IBA 06/2021
1	Immune Checkpoint InhibitorsIBA 06/2021
1	Therapeutic UsesIBA 01/2021
1	cocoa butterIBA 01/2020
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	Fish OilsIBA 01/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020
1	LigandsIBA 01/2019
1	Member 9 Tumor Necrosis Factor Receptor SuperfamilyIBA 01/2019
1	Immunologic Factors (Immunomodulators)IBA 01/2019
1	hemoglobin P (Hb P)IBA 01/2017
1	Delayed-Action PreparationsIBA 01/2017
1	Dextrans (Dextran)FDA Link 08/2015
1	SodiumIBA 08/2015
1	AntigensIBA 07/2015
1	Dextran SulfateIBA 06/2015
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 04/2015
1	Biological ProductsIBA 04/2015
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 04/2015
1	Praziquantel (Biltricide)FDA Link 01/2015
1	AntioxidantsIBA 01/2015
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2011
1	arginine methyl esterIBA 06/2011
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 06/2011
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2011
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2010
1	Tryptophan (L-Tryptophan)FDA Link 01/2010
1	Interleukin-15 (Interleukin 15)IBA 08/2009
1	Bromodeoxyuridine (BrdU)IBA 04/2009
1	PerforinIBA 07/2008
1	beta-Galactosidase (Lactaid)IBA 01/2006
1	Immunoglobulins (Immunoglobulin)IBA 01/2006
1	Abatacept (Orencia)FDA Link 10/2005
1	Monoclonal AntibodiesIBA 10/2005

Therapy/Procedure

17	Therapeutics 06/2021 - 04/2002
14	Microspheres (Microsphere) 10/2020 - 12/2002
8	Immunotherapy 10/2020 - 12/2002
3	Aftercare (After-Treatment) 01/2010 - 02/2004
2	Radiotherapy 10/2019 - 05/2014
2	Neoadjuvant Therapy 10/2019 - 12/2002
2	Injections 12/2004 - 12/2002
1	Chemoprevention 01/2020
1	Intravaginal Administration 01/2018
1	Precision Medicine 06/2015
1	Drug Therapy (Chemotherapy) 01/2015